Thallium-201 scintigraphy | Radiology Reference Article

Thallium-201 (Tl-201) is a radiopharmaceutical used for scintigraphy, primarily of the myocardium. The element thallium is treated by the body as an analog of potassium; it is produced in a cyclotron by bombarding thallium-203 with protons.. Characteristics. thallium is a monovalent cation. usually employed in the form of a …

Functional significance of myocardial perfusion defects …

@article{osti_6170555, title = {Functional significance of myocardial perfusion defects induced by dipyridamole using thallium-201 single-photon emission computed tomography and two-dimensional echocardiography}, author = {Jain, A and Suarez, J and Mahmarian, J J and Zoghbi, W A and Quinones, M.A. and Verani, M S}, …

Thallium-201

Indications for the thallium-201 scan are as follows: FDA Approved Indications. Myocardial imaging: One of its principal uses is in …

The Significance of Thallium-201-Chloride SPECT …

The Significance of Thallium-201-Chloride SPECT Myocardial Perfusion Imaging in the Management of Patients With Stable Chronic Coronary Artery Disease Ivan Jurić, 1 Emir Fazlibegović, 1 Danijel Pravdić, 1 Boris Starčević, 2 Ante Punda, 3 Dražen Huić, 4 Mustafa Hadžiomerović, 1 Damir Rozić, 1 Marko Martinac, 5 Darko Markota ...

Clinical significance of thallium-201 and gallium-67 …

One hundred and thirty-nine patients with pulmonary tuberculosis were evaluated by means of gallium-67 and thallium-201 scintigraphy. The disease was clinically active in 83 and inactive in 56. The uptake ratio between the lesion and the contralateral normal lung field was calculated. The ratio determined by67Ga scintigraphy was expressed as GR, and …

Outcome Significance of Thallium-201 and Iodine-123 …

The relevance of brief antecedent ischemia to preservation of myocyte viability and cardiac function is still controversial in humans. Dysfunctioning but viable myocardium shows impaired fatty acid metabolism despite restored coronary perfusion. We asked whether preinfarction angina might be related to preservation of cell viability and …

Significance of positive or negative thallium-201 …

Myocardial ischemia, fibrosis and infarction may occur in patients with hypertrophic cardiomyopathy (HC) in the absence of epicardial coronary artery disease. To determine their prevalence and relation with common characteristics, stress thallium-201 scintigraphy was performed in 28 patients. Eleven (39%) had positive scans despite normal …

[The clinical significance of reverse redistribution of Tl-201 …

To investigate the significance of Thallium-201 reverse redistribution in the subacute phase, 37 patients with AMI underwent Thallium-201 SPECT at rest a month after the onset. The patients were classified into three groups visually and 19 of 37 patients (51%) showed the persistent defect pattern (Group PD), and the remaining 18 patients (49% ...

[Clinical significance of whole body thallium-201 chloride …

This study attempts to characterize the findings of thallium-201 chloride (201TlCl) uptake in patients with multiple myeloma and to evaluate its clinical significance. Twenty-four patients (including 10 untreated cases, 5 relapsed cases and 9 cases in stable course after initial treatment) were eval …

Adenosine SPECT Thallium Imaging

American Society of Nuclear Cardiology (ASNC) recommend against using adenosine SPECT Tl-201/technetium 99m, dual-isotope (rest-stress), imaging for detecting myocardial ischemia because this protocol has high radiation exposure (up to 23 mSv) compared to other isotopes. [2] Tl-201 is a potassium analog, a radioactive isotope of …

Comparison of Thallium-201 and Gallium-67 Citrate …

Gallium is presently used in the diagnosis of inflammatory, granulomatous, and neoplastic lung disease despite its many logistical problems. In contrast, thallium-201 scintigraphy, which was initially developed for myocardial imaging, offers the principal advantage of immediate imaging and diagnosis although it had not been investigated previously for …

Delayed Redistribution in Thallium 201 SPECT Myocardial

This study evaluates the frequency and significance of this delayed redistribution with SPECT 201 Tl. Patients with either no or incomplete redistribution at 4 h had repeat imaging 18 to 48 h later. Delayed redistribution was seen in 8/26 (31 percent). Four had incomplete and four had no redistribution at 4 h.

Significance of positive or negative thallium-201 …

DOI: 10.1016/0002-9149(89)90428-1 Corpus ID: 28551595; Significance of positive or negative thallium-201 scintigraphy in hypertrophic cardiomyopathy. @article{vonDohlen1989SignificanceOP, title={Significance of positive or negative thallium-201 scintigraphy in hypertrophic cardiomyopathy.}, author={Thomas W. von …

The Significance of Thallium-201-Chloride SPECT …

Stress-MPI is often employed to assess the functional significance of obstructive CAD. It is very useful in cases with a moderate pre-test probability of CAD and in accurately predicting presence of epicardial CAD. 1 Moreover, the left ventricular function may be preserved despite severe coronary stenosis or occlusions in the presence of an …

Outcome significance of thallium-201 and iodine-123 …

Outcome significance of thallium-201 and iodine-123-BMIPP perfusion-metabolism mismatch in preinfarction angina J Nucl Med. 1998 Sep;39(9):1492-9. ... The ratio of the thallium severity index to that of BMIPP at an acute stage was significantly related to improved regional wall motion during follow-up in the reperfused patients (y=-53x + 65, r ...

Physiopathological Significance of Thallium-201 per …

To define the physiopathological significance of 201Tl per rectum scintigraphy, we compared results obtained using this method with direct measurement of inferior mesenteric shunting, portal pressure, liver cellular function as evaluated by the Aminopyrine Breath Test and the size of esophagogastric varices and Spleen, …

The Significance of Thallium-201-Chloride SPECT Myocardial …

Reverse redistribution of 201 Tl on scintigraphic images is a predictor of myocardial viability. Evidence from our study suggests that optimally treated chronic …

Thallium 201 Myocardial Imaging

Thallium is a potassium analogue that has been used to study cellular lesions in myocardial tissue, a tissue with a high potassium content. Using radioactive …

The clinical significance of unusual sites of thallium-201 …

The clinical significance of unusual sites of thallium-201 uptake. GAMUT Edited by Robert C. Stadalnik The Clinical Significance of Unusual Sites of Thallium-201 Uptake Arthur Z. Krasnow, B. David Collier, Ali T. C URRENTLY, Thallium-201 (2°lT1) is the major radionuclide for myocardial perfu- sion imaging. To a lesser extent it is also …

The Significance of Thallium-201-Chloride SPECT Myocardial …

Conclusions: Reverse redistribution of 201 Tl on scintigraphic images is a predictor of myocardial viability. Evidence from our study suggests that optimally treated …

Thallium 201

Thallium-201 is a cyclotron-produced radionuclide that decays by electron capture, with a half-life of about 73 hours. On decay, the major emissions are characteristic x-rays of the daughter product, mercury-201 ( 201 Hg), with an energy range of 69 to 81 keV. These are the primary photons used in myocardial imaging.

(PDF) Outcome significance of thallium-201 and iodine-123 …

The ratio of the thallium severity index to that of BMIPP at an acute stage was significantly related to improved regional wall motion during follow-up in the reperfused patients (y=-53x + 65, r=0 ...

Significance of fill-in after thallium-201 reinjection …

@article{osti_6402612, title = {Significance of fill-in after thallium-201 reinjection following delayed imaging: Comparison with regional wall motion and angiographic findings}, author = {Tamaki, N and Ohtani, H and Yonekura, Y and Nohara, R and Kambara, H and Kawai, C and Hirata, K and Ban, T and Konishi, J}, abstractNote = …

Thallium-201 scintigraphy in bone and soft-tissue tumors: …

Objective: It has been reported that delayed scan of thallium-201 (201Tl) scintigraphy is useful for differentiating malignant tumors from benign lesions and for evaluating treatment response. However, physiological muscle uptake which usually increases in delayed scans, often makes it difficult to evaluate 201Tl uptake and its washout in bone and soft-tissue …

Thallium-201 myocardial scintigraphic evidence of ischemia …

Exercise thallium-201 myocardial images showed minimal reduction of radio-activity in the anterior, apical, antero-lateral and postero-lateral wall. Myocardial thallium-201 washout analysis revealed washout abnormalities all over the left ventricular myocardium similar to those of triple vessel disease, supporting the exercise left ...

Clinical significance of reverse redistribution on technetium …

Reverse redistribution of thallium-201 detected by SPECT imaging after dipyridamole in angina pectoris. Am J Cardiol. 1990 May 15; 65 (18):1176–1180. [Google Scholar] Dey HM, Soufer R. Reverse redistribution on planar thallium scintigraphy: relationship to resting thallium uptake and long-term outcome. Eur J Nucl Med. 1995 Mar; 22 (3):237–242.

Clinical significance of thallium-201 SPECT after …

Clinical significance of thallium-201 SPECT after postoperative radiotherapy in patients with glioblastoma multiforme. Clinical Study – Patient …

To study the efficacy of thallium-201 as tumor seeking …

Introduction. Thallium-201 is a mono-valent radioisotope and has biological properties very similar to potassium. 1, 2 The major role of thallium in nuclear medicine has been in myocardial perfusion imaging, parathyroid imaging and in assessment of viability post myocardial infarction. It was used for tumour imaging in late 1980s and early 1990s.

The Significance of Thallium-201-Chloride SPECT …

The Significance of Thallium-201-Chloride SPECT Myocardial Perfusion Imaging in the Management of Patients With Stable Chronic Coronary Artery Disease. Ivan Jurić. 1, Emir Fazlibegović, Danijel Pravdić. 1, Boris Starčević. 2, Ante Punda. 3, Dražen Huić. 4, Mustafa Hadžiomerović. 1, Damir Rozić. 1, Marko Martinac. 5, Darko Markota. 1 ...

Significance of Positive or Negative Thallium-201 …

Significance of Positive or Negative Thallium-201 Scintigraphy in Hypertrophic Cardiomyopathy Thomas W. von Dohlen, MD, L. Michael ... rent study assesses the utility of thallium-201 myocardi- al scintigraphy for this purpose and relates the presence of perfusion abnormalities to age, chest pain, severity of myocardial hypertrophy, outflow ...

Reverse redistribution of thallium-201 represents a low-risk …

The aim of the study was to evaluate the prevalence and clinical significance of reverse redistribution on thallium-201 imaging in post-myocardial infarction patients who have undergone thrombolytic therapy. Sixty-two patients aged 35-79 (mean 60) years with proven myocardial infarction who had unde …

Myocardial metabolic, hemodynamic, and …

Background: Exercise-induced abnormalities during thallium-201 scintigraphy that normalize at rest frequently occur in patients with hypertrophic cardiomyopathy. However, it is not known whether these abnormalities are indicative of myocardial ischemia. Methods and results: Fifty patients with hypertrophic cardiomyopathy underwent exercise 201Tl …

Slow coronary run-off in patients with angina pectoris: …

Exercise thallium-201 myocardial scintigraphy revealed perfusion abnormalities in 13 (76.4%) patients. We then selected 89 individu … Slow coronary run-off in patients with angina pectoris: clinical significance and thallium-201 scintigraphic study

Hemodynamic significance of increased lung uptake of thallium-201

To determine the hemodynamic significance of increased lung thallium-201 uptake, resting thallium images in 23 normal subjects and 90 patients with various cardiac diseases were reviewed. Significant thallium uptake in the lung was observed in 60 cases and was especially frequently in mitral valvular disease (19 of 19 cases) and in myocardial ...

Adenosine SPECT Thallium Imaging

Tl-201 is a potassium analog, a radioactive isotope of thallium with a half-life of 73 hours, which is up-taken by myocardial …

Clinical significance of thallium-201 single-photon emission

The clinical significance of Thallium-201 single-photon emission computerized tomography (Tl-201 SPECT) in the evaluation of viability of gliomas was studied comparatively with histological examination of tumor tissue using Ki-67 and proliferative cell nuclear antigen (PCNA) monoclonal antibody. The …

[Prognostic significance of large perfusion defects on thallium-201

To evaluate the prognostic significance of perfusion abnormalities, particularly large defects, in dilated cardiomyopathy (DCM), we performed thallium-201 myocardial scintigraphy and 24-hour ambulatory ECG monitoring in 27 patients. The abnormal scintigraphic patterns and the presence of ventricular …